1. Immortalization of cancer cell: Cancer cells are characterized by immortalization; they overcome apoptosis by altering the genes that control such death of the cell. Genetic expressions of certain genes make the malignant cells immortal. These two genes are oncogenes and tumor suppressor gene. Actually activation of protooncogene and inactivation of tumor suppressor genes both [...]
1. The tumor cells are much rounded in shape compared to normal cells. 2. Mitochondrial size is said to be smaller in cancer cells than the normal. In cancer cells, the alternation is extremely frequent mitochondrial swelling and it appears denser. Some granules are smaller than mitochondria, termed as growth granules, which are found only [...]
Cancer cells are defined by two heritable properties: they and their progeny (i) reproduce in defiance of the normal restraints on cell division and (2) invade and colonize territories normally reserved for other cells. The controlling mechanism in the cell proliferation is maintained by a chain of events. Very occasionally, this control breaks down. A [...]
Like other genes, the genes regulating cell divisions are subjected to mutation. This may either stop the division or result in a rapid and uncontrolled division. Cancer is the cumulative effect of several abnormalities resulted from rapid and uncontrolled division of a particular type of cells. Tumour is the formation resulted from abnormal growth and [...]
It is a condition when the regulation of the cell cycle is disrupted and cells divide continously and more rapidly than in normal instances. As a result a tumor or neoplasm , relentlessly growing mass or abnormal cells is produced.
