1. The tumor cells are much rounded in shape compared to normal cells. 2. Mitochondrial size is said to be smaller in cancer cells than the normal. In cancer cells, the alternation is extremely frequent mitochondrial swelling and it appears denser. Some granules are smaller than mitochondria, termed as growth granules, which are found only [...]
Cancer cells are defined by two heritable properties: they and their progeny (i) reproduce in defiance of the normal restraints on cell division and (2) invade and colonize territories normally reserved for other cells. The controlling mechanism in the cell proliferation is maintained by a chain of events. Very occasionally, this control breaks down. A [...]
Like other genes, the genes regulating cell divisions are subjected to mutation. This may either stop the division or result in a rapid and uncontrolled division. Cancer is the cumulative effect of several abnormalities resulted from rapid and uncontrolled division of a particular type of cells. Tumour is the formation resulted from abnormal growth and [...]
It is a condition when the regulation of the cell cycle is disrupted and cells divide continously and more rapidly than in normal instances. As a result a tumor or neoplasm , relentlessly growing mass or abnormal cells is produced.
The current view of cell-cycle control is that transitions between different phases of the cycle-G1, S, G2 and M are regulated by certain “check-points”. Two types of proteins are known to play critical roles. The cyclins and cyclin-dependent kinases or CDKs. One of the important check points lies in mind G1. In tumour cells, checkpoints [...]
Dr. Amlan Kumar Mitra, Biology Guide Since 2009
