What was the Objective of H. J. Muller's Expt. or his CIB technique?

1. He first demonstrated that mutations could be induced by external factor such as X- rays.

2. X-ray treatment markedly increased the frequently of sex-linked recessive lethal mutations in D. melanogaster.

3. Detection of X-linked lethals is unambigious and error free- simply scoring for the presence or absence of male progeny.

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  1. Lethal mutations

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